February 5, 2023

Best Full-Spectrum CBD Oil: Top 7 Brands of 2021

Now, more than ever, more people are using CBD to help with many different health issues from anxiety, to depression, insomnia, chronic pain, sleep, and many more. But with so many brands and products out there, it can be difficult to not only tell which brands are the best, but also what products are the cleanest and most potent. If you’re like most people who are first-time CBD users, then chances are, you have a lot of questions about what full-spectrum CBD is, how it works to help with different health issues, and which brands are the best ones to buy full-spectrum CBD products from.

Our guide to the best full-spectrum CBD oil will point you in the right direction and help answer some questions you may have about CBD, its benefits, some of the differences between full-spectrum, broad-spectrum, and CBD isolate oils, how to use full-spectrum oil, and much more. We’ll also be giving you key details on our top seven best full-spectrum CBD oil brands for 2021. To start with, please read on to find our top seven brands below.

Top 7 Full-Spectrum CBD Oil Brands in 2021

  1. FAB CBD — Most Potent Full-Spectrum

2. Premium Jane — Premium CBD Oil

3. CBDPure — Highest Organic Standards

4. Nuleaf Naturals — Pure and Potent Oils

5. PlusCBD — Innovative Products

6. Green Roads — Pharmacist Formulated Oils

7. Lazarus Naturals — High-Quality CBD Oil

How We Came Up with Our List of Full-Spectrum CBD Oils

When it came time to compile a list of the top full-spectrum CBD oil brands, we first needed to construct strong guidelines and strict criteria to measure each brand up against. Next, we gathered the names of the most popular brands in the CBD oil market. And because there are quite a few brands out there, our list quickly grew unmanageable. However, once we held each brand up against our guidelines, as well as looked at verified customer reviews, where the brands sourced their hemp from, how each brand crafted its products, and whether the brands used third-party labs to test their products, we were able to dramatically cut the list down until we were left with our top seven brands.

Our ultimate goal through writing this guide was to present our readers with the best full-spectrum CBD oil brands without further overwhelming them. In order to get down to our top seven choices, we also read industry expert reviews and the writings of respected CBD journalists and niche experts.

What You Should Look for When Buying Full-Spectrum CBD Oil

If you plan on doing further research of your own into CBD oil brands and full-spectrum oils, then you might want to consider looking into:

  • How strong each brand’s full-spectrum oil was at helping to calm and control various health issues.
  • How each brand processed and extracted its hemp.
  • If the brand follows FDA guidelines.
  • Whether the oils were full-spectrum, broad-spectrum, or CBD isolate.
  • If the oils contained 0.3% or less THC in accordance with federal law.
  • If third-party lab reports are easy for customers to find.
  • If instructions for oil use were clearly listed and easy for customers to understand.
  • Overall brand reputation among customers and industry experts.

7 Best Full-Spectrum CBD Oils in 2021

Courtesy of SmarterCBD

The FAB CBD team uses science and innovation to create clean and potent products for its customers. All of the brand’s organic hemp is grown and harvested in Colorado. In order to get the cleanest and purest extracts, FAB CBD uses the industry preferred CO2 extraction method. Every one of the brand’s products is regularly tested by an independent third-party lab, and those reports are then published on the FAB CBD website where customers can easily find them. Since its inception in 2017, the brand has upheld its mission of creating premium supplementation so that customers can live a preventative wellness lifestyle.

When it comes to full-spectrum CBD oils, FAB CBD stops at nothing to make sure its oils are potent, effective, and clean. The brand’s oils come in strengths of 300mg, 600mg, 1200mg, and 2400mg, and in smooth, bright flavors like vanilla, citrus, berry, natural, and mint. FAB CBD also just recently came out with a 2400mg CBD+CBG Oil in mint and citrus flavors. The oil is a 1:1 ratio of CBD to CBG, which means you’re getting 1200mg of CBD and 1200mg of CBG per bottle.


  • Clean and effective full-spectrum CBD oils
  • Oils are naturally flavored
  • Highly responsive and caring customer service department
  • Innovative products
  • Strong belief in transparency
  • Organic hemp that’s grown in Colorado
  • CO2 extraction
  • Regular third-party lab testing of its products


  • A solid variety of full-spectrum CBD oils that customers love
  • Affordable prices
  • Clean hemp extracts
  • Delicious, natural oil flavors


  • The brand does not offer international shipping

Premium Jane consistently works hard to make sure its customers know about CBD’s healing benefits through the promotion of its top-quality products. All of Premium Jane’s products are created using regulated Kentucky hemp. The brand next obtains all of its hemp extracts through the CO2 extraction process. Before the products are put up for sale, they are tested by an independent third-party lab. Premium Jane prides itself on creating interesting CBD products that customers love.

Premium Jane makes full-spectrum CBD tinctures in 1000mg, 600mg, and 300mg Citrus flavor, Mint flavor, Natural flavor, and Mint Chocolate flavor. Additionally, the brand also makes 3000mg and 1000mg tinctures in Lemon Lime and Peach Nectar flavors.


  • Premium full-spectrum CBD oils in an array of strengths and flavors
  • Third-party lab testing
  • Uses CO2 extraction process
  • Regulated hemp from Kentucky
  • Affordable prices
  • Worldwide shipping


  • Offers free shipping
  • Products regularly tested by an independent lab
  • Strong variety of full-spectrum CBD tinctures


  • Lack of gluten-free products

CBDPure was founded in 2016 with a mission to make the best quality CBD oil that’s supported by third-party lab reports and a 90-day, money-back guarantee. To that end, the brand is strongly committed to purity and creates its full-spectrum oils using only high-potency cannabidiol and a base of unprocessed natural hemp oil. All of the CBDPure’s hemp is organic, natural, and is grown in Colorado using organic farming techniques and minimal processing. When the brand harvests its hemp, the crop is tested for chemicals and heavy metals. Once dried and cut, the CO2 extraction method is used to obtain CBDPure’s extracts.

Compared to other brands, CBDPure’s selection of full-spectrum oils is quite limited. The brand makes unflavored full-spectrum oils in strengths of 300mg, 600mg, and 1000mg. Every potency of the brand’s oil is made from organic hemp plants and is tested by an independent lab.


  • Organic Colorado hemp
  • Clean farming methods
  • Co2 extraction process
  • Third-party lab testing


  • Easily accessible lab reports
  • Offers international shipping
  • Products available online and in stores


NuLeaf Naturals has been committed to making high-quality, pure, and potent CBD products since 2014. All of the brand’s full-spectrum hemp is free from additives or harmful chemicals. The brand’s mission is to create products that everyone at NuLeaf Naturals and their families and friends would use. NuLeaf Naturals creates safe, effective, and consistent CBD products that are tested by third-party labs to confirm that they are free from pesticides, mold, herbicides, heavy metals, fungi, and mycotoxins. All of the hemp that NuLeaf Naturals uses to make its products are organic, clean, and grown in the USA.

Like CBDPure, NuLeaf Naturals’ full-spectrum CBD oils are also limited, though the brand does also create CBC, CBG, and CBN oil varieties as well. NuLeaf Naturals makes an unflavored full-spectrum CBD oil in 300mg, 900mg, 1800mg, 3000mg, and 6000mg strengths, as well as a full-spectrum CBD, CBC, CBG, and CBN Multi-Cannabinoid oil in 300mg, 900mg, and 1800mg.


  • Creates high-quality, organic CBD products
  • Third-party lab testing
  • Interesting variety of oils


  • CBD oil discount programs
  • CBD products contain high levels of CBD
  • GMP (Good Manufacturing Practices) compliant and has an ISO 8-certified lab


  • Only makes unflavored CBD oils
  • Limited product variety

Since 2012, PlusCBD’s mission has been to improve the wellbeing of both people and of the planet. The brand believes in the unlimited future of hemp and strives to improve the health and prosperity of its customers, employees, and communities. PlusCBD uses agricultural hemp grown in Europe to create all of its products. The brand then uses the CO2 extraction method to obtain all of its full-spectrum extracts. Lastly, all of PlusCBD’s products are tested by a third-party lab.

PlusCBD has an interesting selection of full-spectrum CBD Drops including 750mg, 1500mg, and 3000mg strength drops in Dark Chocolate Mint flavor, and 750mg and 1500mg strength drops in Lemon Ginger flavor, 250mg, 750mg, and 1500mg strength unflavored drops, 250mg, 750mg, and 1500mg drops in Peppermint flavor, and 500mg drops in Unsweetened Original Formula.


  • Uses nutrient-rich hemp that’s grown outdoors using renewable and sustainable methods
  • Uses EU-certified hemp seeds
  • Third-party lab testing
  • CO2 extraction


  • Gluten-free products
  • US and international shipping
  • Affordable prices


  • Lack of information as to exactly where the hemp is sourced

Green Roads was started by Laura Fuentes, a compounding pharmacist, in 2013. Fuentes had been working as a pharmacist for 25 years when her dear friend came to her with his health struggles. Together, the two set out to create a line of CBD products that could help the health and wellbeing of everyone. To this day, Green Roads has three pharmacists on staff that oversee product formulation and manufacturing. The brand makes full-spectrum, broad-spectrum, and CBD isolate products.

Green Roads makes Apple Kiwi Bliss Broad Spectrum CBD Oil in 1500mg, 750mg, and 300mg, Full-Spectrum CBD Oil in 1500mg, 750mg, and 300mg, Broad Spectrum CBD Oil in 1500mg, 750mg, and 300mg, Mint Breeze Broad Spectrum Oil in 1500mg, 750mg, and 300mg, and Sweet Sleep CBD Oil in 750mg.


  • Pharmacist formulated products
  • Independent lab testing
  • US-grown hemp
  • Diverse CBD oil offerings


  • Award-winning products
  • Easily accessible third-party lab reports
  • Free shipping
  • Rewards and referral programs


  • No international shipping
  • Lack of information on hemp sources

Lazarus Naturals has been dedicated to creating effective, top-quality, affordable CBD products. The brand was founded on the strong belief that CBD can have a positive impact on people’s quality of life. Lazarus Naturals’ founders also believe that CBD should be easily accessible to everyone. All of the brand’s hemp is organic and grown in Central Oregon, is thoroughly tested for heavy metals, pesticides, and potency level, and is extracted using a cryogenic ethanol extraction process. Each product is then routinely tested by an independent third-party lab for residual solvents, heavy metals, pesticides, microbial impurities, and overall potency level.

Lazarus Naturals makes:

  • Chai Tea Latte flavor Full Spectrum, High Potency CBD Oil Tincture in 3000mg
  • Classic flavor Full Spectrum, High Potency CBD Oil Tincture in 750mg, 1500mg and 3000mg
  • Chocolate Mint Full Spectrum, High Potency CBD Oil Tincture in 750mg, 1500mg, 3000mg, and 6000mg
  • French Vanilla Mocha flavor Full Spectrum, High Potency CBD Oil Tincture in 750mg, 1500mg, 3000mg, and 6000mg
  • Yuzu flavor Full Spectrum, High Potency CBD Oil Tincture in 1500mg, 3000mg, and 6000mg
  • Blood Orange flavor THC-Free, High Potency CBD Oil Tincture in 750mg, 1500mg, and 3000mg
  • Flavorless THC Free, High Potency CBD Oil Tincture in 750mg, 1500mg, and 3000mg
  • Wintermint flavor THC Free, High Potency CBD Oil Tincture in 750mg, 1500mg, and 3000mg
  • Classic Full Spectrum, Standard Potency CBD Oil Tincture in 600mg, 1200mg, and 2400mg
  • Yuzu flavor Full Spectrum, Standard Potency CBD Oil Tincture in 600mg
  • Classic Full Spectrum, High Potency CBD Oil Tincture in 6000mg


  • Large selection of CBD oils in a variety of strengths and flavors
  • Financial assistance programs
  • The brand is a member of industry organizations


  • Offers a 60% discount to veterans, the disabled, and low-income individuals
  • Unique product variety


  • A large selection of oils can be overwhelming to new customers
  • No international shipping

Courtesy of SmarterCBD

Difference Between Full-Spectrum, Broad Spectrum, and CBD Isolate Oils

If you are new to the world of CBD, then you might not quite understand the differences between the various CBD varieties. Typically, CBD oils and tinctures come in full-spectrum, broad-spectrum, and CBD isolate options. Full-spectrum oils contain all of the beneficial cannabinoids, terpenes, and phytonutrients of the hemp plant. These types of oils also contain low amounts of THC or tetrahydrocannabinol. Along with CBD, THC is another one of the main cannabinoids in the hemp and marijuana plants. However, since the hemp plant naturally contains very little THC, 0.3% or less, in fact, there is no way that anyone can get high from hemp-derived CBD oils.

Broad-spectrum oils are very much the same as full-spectrum oils, however, they do not contain any THC. All of the THC in broad-spectrum oils has been filtered out, leaving many of the same cannabinoids, terpenes, and phytonutrients as full-spectrum oils. Broad-spectrum oils are a great option for people who are worried about potentially receiving a false positive on a drug test but still want to receive many of the same benefits as those who take full-spectrum oils do. Lastly, in CBD isolate oils, all of the plant components have been filtered out through a special process. What’s left is 99% pure CBD in the final product.

What Research Says About Full-Spectrum CBD

Full-spectrum CBD contains a wealth of benefits that can positively impact overall health and wellness. In fact, full-spectrum oils are loaded with cannabinoids, terpenes, flavonoids, and cannaflavins. Read on to learn more about these beneficial compounds.


Cannabinoids are naturally occurring compounds — like CBD, THC, CBG, CBN — that are found in the hemp and marijuana plants. While there are well over 400 compounds in the cannabis Sativa plant, only about 66 of them are considered cannabinoids. Cannabinoids function in the human body by working with the CB1 and CB2 receptors in the endocannabinoid system, or ECS, which helps to bring the body back into a state of homeostasis. The way in which the cannabinoids affect the body depends on which cannabinoid receptors they’re binding to. Interestingly, scientists believe that CBD works to quell anxiety and also helps to lower THC’s psychoactive effects.

Cannaflavins and Flavonoids

Cannaflavins are flavonoids that are found in the cannabis plant. Scientists think that cannaflavins are so powerful because they have anti-inflammatory effects that are better than aspirin.

Flavonoids are similar to terpenes in that they affect how cannabis smells and tastes. Additionally, they also shield plants from disease and harmful UV rays. In essence, flavonoids help to protect plants and guarantee their survival.


Terpenes cause plants to give off certain scents. They also are responsible for how CBD will affect you. Two main terpenes are myrcene and limonene, and when they work in conjunction with CBD, they bind to the neurotransmitters in the brain. Just as there are different strains of cannabis, there are also different strains of terpenes. Therefore, while some terpenes aid in relaxation, others can cause you to feel energized.

What is the Entourage Effect?

One of the main reasons why a lot of people choose full-spectrum CBD oils over broad-spectrum or CBD isolate oils is that CBD and THC work together to create an entourage effect. The entourage effect has a way of positively affecting the body’s endocannabinoid system that works to regulate functions and processes like:

  • Mood
  • Appetite
  • Sleep
  • Memory
  • Fertility
  • Pain
  • Reproduction

In the entourage effect, the CBD and THC in full-spectrum CBD oil work to boost each other’s positive properties while lowering one another’s negative properties. In fact, scientists recently found that taking full-spectrum oils has more benefits than taking CBD and THC in isolation from each other. Additionally, THC, CBD, terpenes, flavonoids, cannabinoids, and other compounds work together to produce a stronger effect than if they were used in isolation. When someone takes full-spectrum CBD oil, it works to help boost the body’s endocannabinoid system so that the body can return to a state of balance.

Interestingly, a study conducted in 2011 discovered that a combination of cannabinoids and terpenes could work together to help reduce:

  • Pain
  • Epilepsy
  • Anxiety
  • Inflammation

Even though some people experience adverse reactions from THC, when CBD is added into the mix, it helps to reduce many of the negative side effects of the THC including nausea, hunger, sleepiness, and anxiety. Moreover, a study conducted in 2018 discovered that some of the terpenes and flavonoids in full-spectrum oils may have anti-inflammatory and neuroprotective properties. In essence, the study is saying that these compounds could boost the therapeutic potential of CBD.

Courtesy of SmarterCBD

What are the Benefits of Full-Spectrum CBD Products?

Full-spectrum CBD oils have a wealth of benefits associated with them due to the number of cannabinoids, terpenes, and phytonutrients they contain. Continued research confirms that full-spectrum CBD products can help reduce the symptoms of different health issues so that they can potentially be controlled over time. Some of the conditions that full-spectrum CBD products can help with are:

Full-spectrum CBD users have found success in lowering their chronic pain and inflammation through regular and consistent use of CBD oil. Moreover, a host of studies regarding full-spectrum CBD’s positive effects against different health issues are proving that the oil is extremely successful and effective at helping with a good deal of hard-to-treat conditions. Along with cannabinoids and terpenes, full-spectrum CBD oil also consists of fatty acids, protein, minerals, and fiber, giving it a well-rounded nutritional profile. Therefore, full-spectrum CBD oils can also have nourishing effects along with their anti-inflammatory, anti-nausea, and pain-relieving properties.

Some of the many benefits of full-spectrum CBD oil include:

  • Pain relief
  • Lowered muscle cramping
  • Better sleep
  • Lessened insomnia
  • Lowered nausea
  • An increased appetite (if your appetite has been suppressed)

Indeed, there are many wonderful reasons to choose full-spectrum products over broad-spectrum or CBD isolate ones. At the end of the day, however, it’s up to you to decide which variety will work best for your health goals and wellness needs.

Are There Any Adverse Effects Associated with Full-Spectrum CBD?

CBD in general — whether full-spectrum, broad-spectrum, or CBD isolate — has very few adverse effects associated with it. Moreover, the side effects linked to CBD are extremely mild. Some common side effects of CBD include:

  • Dizziness
  • Low blood pressure
  • Nausea
  • Drowsiness
  • Changes in appetite
  • Changes in weight

As with any new addition to your existing supplement regimen, you should speak with your doctor or prescribing physician if you have questions or concerns. When it comes to prescription medication and CBD, if your medication has a “Grapefruit Warning” listed on the label, then you need to speak with your doctor. Much like grapefruit juice, grapefruit, and other citrus fruit, CBD also contains compounds that can interfere with the way the body metabolizes certain prescription medications. Specifically, grapefruit and CBD can neutralize enzymes in the gut that help break down and eliminate medications. When this happens, too much medication enters into the liver and cannot be processed properly, leaving too much medication to enter into the bloodstream. The end result is dangerously high levels of medication in the body. Another scenario is that low doses of medications can turn into high doses of medications if grapefruit or CBD is taken with them.

Courtesy of SmarterCBD


What is Full Spectrum CBD Oil?

Full-spectrum CBD oil is a variety of oil that contains CBD, THC, and other cannabinoids, terpenes, and phytonutrients.

When Should I Use Full-Spectrum CBD Oil?

Full-spectrum CBD oil should be used regularly and consistently. In order to receive the most benefits out of the CBD, you should take the oil at the same time(s) each and every day. Consistency, patience, and time are key when it comes to establishing a successful full-spectrum CBD oil routine.

How to Use Full Spectrum CBD Oil?

The best rule of thumb to follow when it comes to taking full-spectrum oil is to start at a low dose and then slowly increase over time. For example, if you’ve purchased a 600mg bottle of FAB CBD’s full-spectrum oil, begin by taking half a dropper full once a day. This will equal 10mg of CBD oil. Stay with this dose for about one week before checking in with yourself to see how you feel. This is also the perfect time to keep a journal so that you can properly document anything you are experiencing or feeling while on a specific CBD oil dose. If after one week you feel like you need to increase, then go up to a half dropper full twice a day. This will now equal 10mg of CBD oil twice a day, or 20mg of oil a day. Stick with this dose for another week before checking in again. If you feel the need to increase your dose again, follow the same pattern as described above.

Will Full-Spectrum CBD Oil Make You High?

The short response to the question is that you can’t get “high” from full-spectrum CBD oil. The long response is that because of the 2018 Farm Bill, all CBD products derived from hemp are legal across the United States. The bill states that all hemp-based products must contain 0.3% or less THC in order to be sold and bought within the US. And since the hemp plant naturally contains low levels of THC, there is no way that anyone can get “high” from full-spectrum CBD oils.

Is it Legal to Buy CBD Oil?

The 2018 Farm Bill made it legal to sell and buy hemp-based CBD products across the United States, providing they contain 0.3% or less THC. So, whether you’re purchasing CBD online or visiting a local brick-and-mortar location, you can take comfort in the fact that you will be able to legally buy any type of hemp-derived full-spectrum CBD oil that you’re interested in.

Courtesy of SmarterCBD

Final Thoughts: Why Full-Spectrum CBD Oil is the Best Option

If you’re just starting out in your search for the best full-spectrum CBD oil for yourself, then it pays to take the time to research all of the things you want answers to. And because the CBD market is flooded with brands, it may take you some time to find the exact product you’re looking for. A great place to start, however, is by jumping online to visit our top seven brands for the best full-spectrum CBD oil. While you’re examining CBD oil products, you’ll notice that there are full-spectrum, broad-spectrum, and CBD isolate options. Even though all three of these types have their own set of benefits, full-spectrum oils have the most documented positive effects on customers with difficult health issues.

Unlike CBD isolate oils, full-spectrum CBD oils contain CBD, THC, terpenes, cannabinoids, and other phytonutrients that work with the body’s endocannabinoid system to help bring it back into a state of balance. Moreover, these same components in full-spectrum oils create an entourage effect to help boost each other’s positive effects while lowering one another’s negative properties. In fact, a host of scientific studies speak to CBD’s effectiveness in calming down the symptoms associated with depression, anxiety, chronic pain, sleep issues, insomnia, and others.

If you’re interested in buying a full-spectrum CBD oil, you should always check that the product contains 0.3% or less THC. This will confirm to you that the oil falls within the legal guidelines set forth by the 2018 Farm Bill. Next, make sure that the brand you’re interested in practices transparency by having all of its products tested by an independent third-party lab and then publishing those results on its website. The brand should also give customers factual information about CBD by clearly stating what it is, what its benefits are, and how it can help with various health and wellness issues. Lastly, if you’ve got questions or concerns about CBD, then don’t hesitate to reach out to your primary care doctor or medical specialist.

Best Full-Spectrum CBD Oil: Top 7 Brands of 2021